Methotrexate

Methotrexate

Basic Information:

• Chemical Name: Methotrexate
• CAS Number: 59-05-2
• Molecular Formula: C₂₀H₂₂N₈O₅
• Molar Mass: 454.44 g/mol
• Product Code: M813626
• Pack Size: 1 g

Product Description:

• Methotrexate is an antimetabolite and antifolate drug commonly used in chemotherapy, autoimmune diseases, and ectopic pregnancies. It works by inhibiting dihydrofolate reductase, preventing DNA synthesis and cell replication, particularly in rapidly dividing cells.

Storage and Handling:

• Store in a cool, dry place, protected from light.
• Keep the container tightly closed to prevent contamination.
• Handle with care, using gloves and protective clothing to avoid direct contact.

Safety Information:

• Hazards: Highly toxic; may cause severe skin, eye, or respiratory irritation. Can be teratogenic and carcinogenic.
• Precautions: Use full PPE, including gloves, a lab coat, and safety glasses. Handle in a fume hood if possible.

First Aid:

• Skin contact: Wash immediately with plenty of soap and water.
• Eye contact: Rinse cautiously with water for several minutes; remove contact lenses if present.
• Inhalation: Move to fresh air; seek medical attention if symptoms persist.
• Ingestion: Seek immediate medical attention; do not induce vomiting unless instructed by a physician.