Trifluoroacetic acid (TFA)

Trifluoroacetic Acid (TFA)

Basic Information:

• Product Code: T818778

• Pack Size: 100 mL

• CAS Number: 76‑05‑1

• Molecular Formula: C₂HF₃O₂

• Molar Mass: 114.02 g/mol

• Appearance: Colorless liquid

• Odor: Pungent, acidic

• Purity: Laboratory / Analytical Grade

Product Description:

• Trifluoroacetic acid (TFA) is a strong, volatile carboxylic acid widely used in chemical laboratories. Its trifluoromethyl group gives it high acidity and makes it miscible with both water and organic solvents.

Applications:

• Peptide Synthesis: Used as a deprotecting agent to cleave protecting groups.
• Organic Synthesis: Acts as a strong acid catalyst in various reactions.
• Chromatography: Serves as an ion-pairing reagent for HPLC.
• Analytical Chemistry: Used in sample preparation for NMR, MS, and other techniques.

Safety:

• Highly corrosive; causes severe skin burns and eye damage.
• Harmful if inhaled.
• Use gloves and eye protection, and handle in a fume hood.